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mouse glioma cell lines gl261  (Ubigene Biosciences Co Ltd)
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Ubigene Biosciences Co Ltd mouse glioma cell lines gl261
Mouse Glioma Cell Lines Gl261, supplied by Ubigene Biosciences Co Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cell lines gl261 dsmz  (DSMZ)
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Cell Lines Gl261 Dsmz, supplied by DSMZ, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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murine gbm cell line gl261  (Beijing Tiantan Biological)
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Beijing Tiantan Biological murine gbm cell line gl261
scRNA-Seq of <t>GL261-derived</t> tumor in C57BL/6J mice. (A) Schematic of the single-cell sequencing workflow: Mice with GL261-luc orthotopic tumors were divided into two groups: Control administered with 0.9% normal saline via tail vein injection and clofoctol-treated (Clo-treated) administered with 10 mg/kg clofoctol for 10 days. Tumors were then harvested and processed for single-cell RNA sequencing. Figure created by BioRender.com. (B, C) The representative luciferase images (B) and total flux [P/S] of mice on D1 and D10 from treated (C) (mean ± SEM, n = 8). The unpaired Student’s t-test determined the significance level. * P < .05. (D) UMAP visualization colored by sample. (E) UMAP visualization colored by Seurat_clusters. (F) UMAP visualization colored by cell type in clofotcol and control group. (G) VlnPlot showing AUCell score of cell functional status gene sets in Clo-treated and control glioma cells.
Murine Gbm Cell Line Gl261, supplied by Beijing Tiantan Biological, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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murine gbm cell line gl261 - by Bioz Stars, 2026-10
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gl261 murine glioma cell line  (DSMZ)
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DSMZ gl261 murine glioma cell line
scRNA-Seq of <t>GL261-derived</t> tumor in C57BL/6J mice. (A) Schematic of the single-cell sequencing workflow: Mice with GL261-luc orthotopic tumors were divided into two groups: Control administered with 0.9% normal saline via tail vein injection and clofoctol-treated (Clo-treated) administered with 10 mg/kg clofoctol for 10 days. Tumors were then harvested and processed for single-cell RNA sequencing. Figure created by BioRender.com. (B, C) The representative luciferase images (B) and total flux [P/S] of mice on D1 and D10 from treated (C) (mean ± SEM, n = 8). The unpaired Student’s t-test determined the significance level. * P < .05. (D) UMAP visualization colored by sample. (E) UMAP visualization colored by Seurat_clusters. (F) UMAP visualization colored by cell type in clofotcol and control group. (G) VlnPlot showing AUCell score of cell functional status gene sets in Clo-treated and control glioma cells.
Gl261 Murine Glioma Cell Line, supplied by DSMZ, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse high grade glioma cell line gl261  (Beijing Tiantan Biological)
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scRNA-Seq of <t>GL261-derived</t> tumor in C57BL/6J mice. (A) Schematic of the single-cell sequencing workflow: Mice with GL261-luc orthotopic tumors were divided into two groups: Control administered with 0.9% normal saline via tail vein injection and clofoctol-treated (Clo-treated) administered with 10 mg/kg clofoctol for 10 days. Tumors were then harvested and processed for single-cell RNA sequencing. Figure created by BioRender.com. (B, C) The representative luciferase images (B) and total flux [P/S] of mice on D1 and D10 from treated (C) (mean ± SEM, n = 8). The unpaired Student’s t-test determined the significance level. * P < .05. (D) UMAP visualization colored by sample. (E) UMAP visualization colored by Seurat_clusters. (F) UMAP visualization colored by cell type in clofotcol and control group. (G) VlnPlot showing AUCell score of cell functional status gene sets in Clo-treated and control glioma cells.
Mouse High Grade Glioma Cell Line Gl261, supplied by Beijing Tiantan Biological, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gl261 mouse cell line  (Beijing Tiantan Biological)
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Beijing Tiantan Biological gl261 mouse cell line
scRNA-Seq of <t>GL261-derived</t> tumor in C57BL/6J mice. (A) Schematic of the single-cell sequencing workflow: Mice with GL261-luc orthotopic tumors were divided into two groups: Control administered with 0.9% normal saline via tail vein injection and clofoctol-treated (Clo-treated) administered with 10 mg/kg clofoctol for 10 days. Tumors were then harvested and processed for single-cell RNA sequencing. Figure created by BioRender.com. (B, C) The representative luciferase images (B) and total flux [P/S] of mice on D1 and D10 from treated (C) (mean ± SEM, n = 8). The unpaired Student’s t-test determined the significance level. * P < .05. (D) UMAP visualization colored by sample. (E) UMAP visualization colored by Seurat_clusters. (F) UMAP visualization colored by cell type in clofotcol and control group. (G) VlnPlot showing AUCell score of cell functional status gene sets in Clo-treated and control glioma cells.
Gl261 Mouse Cell Line, supplied by Beijing Tiantan Biological, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gl261 mouse cell line - by Bioz Stars, 2026-10
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murine glioma cell line gl261  (DSMZ)
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DSMZ murine glioma cell line gl261
scRNA-Seq of <t>GL261-derived</t> tumor in C57BL/6J mice. (A) Schematic of the single-cell sequencing workflow: Mice with GL261-luc orthotopic tumors were divided into two groups: Control administered with 0.9% normal saline via tail vein injection and clofoctol-treated (Clo-treated) administered with 10 mg/kg clofoctol for 10 days. Tumors were then harvested and processed for single-cell RNA sequencing. Figure created by BioRender.com. (B, C) The representative luciferase images (B) and total flux [P/S] of mice on D1 and D10 from treated (C) (mean ± SEM, n = 8). The unpaired Student’s t-test determined the significance level. * P < .05. (D) UMAP visualization colored by sample. (E) UMAP visualization colored by Seurat_clusters. (F) UMAP visualization colored by cell type in clofotcol and control group. (G) VlnPlot showing AUCell score of cell functional status gene sets in Clo-treated and control glioma cells.
Murine Glioma Cell Line Gl261, supplied by DSMZ, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cell+lines+gl261/GL-261/pm41155935-66-1-17
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murine glioma cell line gl261 - by Bioz Stars, 2026-10
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mouse glioma cell line gl261  (Creative Biolabs)
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Creative Biolabs mouse glioma cell line gl261
scRNA-Seq of <t>GL261-derived</t> tumor in C57BL/6J mice. (A) Schematic of the single-cell sequencing workflow: Mice with GL261-luc orthotopic tumors were divided into two groups: Control administered with 0.9% normal saline via tail vein injection and clofoctol-treated (Clo-treated) administered with 10 mg/kg clofoctol for 10 days. Tumors were then harvested and processed for single-cell RNA sequencing. Figure created by BioRender.com. (B, C) The representative luciferase images (B) and total flux [P/S] of mice on D1 and D10 from treated (C) (mean ± SEM, n = 8). The unpaired Student’s t-test determined the significance level. * P < .05. (D) UMAP visualization colored by sample. (E) UMAP visualization colored by Seurat_clusters. (F) UMAP visualization colored by cell type in clofotcol and control group. (G) VlnPlot showing AUCell score of cell functional status gene sets in Clo-treated and control glioma cells.
Mouse Glioma Cell Line Gl261, supplied by Creative Biolabs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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scRNA-Seq of GL261-derived tumor in C57BL/6J mice. (A) Schematic of the single-cell sequencing workflow: Mice with GL261-luc orthotopic tumors were divided into two groups: Control administered with 0.9% normal saline via tail vein injection and clofoctol-treated (Clo-treated) administered with 10 mg/kg clofoctol for 10 days. Tumors were then harvested and processed for single-cell RNA sequencing. Figure created by BioRender.com. (B, C) The representative luciferase images (B) and total flux [P/S] of mice on D1 and D10 from treated (C) (mean ± SEM, n = 8). The unpaired Student’s t-test determined the significance level. * P < .05. (D) UMAP visualization colored by sample. (E) UMAP visualization colored by Seurat_clusters. (F) UMAP visualization colored by cell type in clofotcol and control group. (G) VlnPlot showing AUCell score of cell functional status gene sets in Clo-treated and control glioma cells.

Journal: Neuro-Oncology Advances

Article Title: Clofoctol as a novel senolytic drug eliminating therapy-induced senescent glioma cells

doi: 10.1093/noajnl/vdag102

Figure Lengend Snippet: scRNA-Seq of GL261-derived tumor in C57BL/6J mice. (A) Schematic of the single-cell sequencing workflow: Mice with GL261-luc orthotopic tumors were divided into two groups: Control administered with 0.9% normal saline via tail vein injection and clofoctol-treated (Clo-treated) administered with 10 mg/kg clofoctol for 10 days. Tumors were then harvested and processed for single-cell RNA sequencing. Figure created by BioRender.com. (B, C) The representative luciferase images (B) and total flux [P/S] of mice on D1 and D10 from treated (C) (mean ± SEM, n = 8). The unpaired Student’s t-test determined the significance level. * P < .05. (D) UMAP visualization colored by sample. (E) UMAP visualization colored by Seurat_clusters. (F) UMAP visualization colored by cell type in clofotcol and control group. (G) VlnPlot showing AUCell score of cell functional status gene sets in Clo-treated and control glioma cells.

Article Snippet: Murine GBM cell line GL261 and the patient-derived glioma cell line T3-5 were obtained from Beijing Tiantan Hospital.

Techniques: Derivative Assay, Single Cell, Sequencing, Control, Saline, Injection, RNA Sequencing, Luciferase, Functional Assay

The clofoctol is more sensitive to senescent glioma cells. (A) Cellular senescence was measured by flow cytometry via senescence probe staining. (B) SA-β-gal was assessed via X-gal staining in glioma cells. Scale bar 200 μm. * P < .05, ** P < .01, *** P < .001, **** P < .0001 by one-way ANOVA with Tukey’s multiple comparison test. (C) RT-qPCR analysis of SASP genes in glioma cells. The data are presented as the means ± SDs. * P < .05, ** P < .01, *** P < .001, **** P < .0001 by one-way ANOVA with Tukey’s multiple comparison test. (D) Western blot analysis of P21 protein in GL261, LN229, and T3-5 cells. (E) Dose-response curves for Clofoctol in senescent glioma cells.

Journal: Neuro-Oncology Advances

Article Title: Clofoctol as a novel senolytic drug eliminating therapy-induced senescent glioma cells

doi: 10.1093/noajnl/vdag102

Figure Lengend Snippet: The clofoctol is more sensitive to senescent glioma cells. (A) Cellular senescence was measured by flow cytometry via senescence probe staining. (B) SA-β-gal was assessed via X-gal staining in glioma cells. Scale bar 200 μm. * P < .05, ** P < .01, *** P < .001, **** P < .0001 by one-way ANOVA with Tukey’s multiple comparison test. (C) RT-qPCR analysis of SASP genes in glioma cells. The data are presented as the means ± SDs. * P < .05, ** P < .01, *** P < .001, **** P < .0001 by one-way ANOVA with Tukey’s multiple comparison test. (D) Western blot analysis of P21 protein in GL261, LN229, and T3-5 cells. (E) Dose-response curves for Clofoctol in senescent glioma cells.

Article Snippet: Murine GBM cell line GL261 and the patient-derived glioma cell line T3-5 were obtained from Beijing Tiantan Hospital.

Techniques: Flow Cytometry, Staining, Comparison, Quantitative RT-PCR, Western Blot